COST Programme
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Friday, 19th April 2013
| 10:00 — 19:00 | Registration |
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OREA Hotel Pyramida, Prague, Reception Foyer |
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| 14:00 — 14:30 | Opening, organizational information and information from COST |
| Bruce Turnbull & Vladimír Křen & Ladislav Petruš | |
| OPENING LECTURE Conference Room III | |
|---|---|
| Chairperson: Bruce Turnbull, UK | |
| 14:30 — 15:10 | Development of new biocatalysts for the synthesis of rare furanosides |
| Richard Daniellou & Vincent Ferrieres, France | |
|
Keynote lecture |
|
| PRESENTATION OF THE NEW GROUP IN THE COST ACTION MULTIGLYCONANO CM1102 Conference Room III | |
| 15:10 — 15:30 | Differences in the mesoscopic structures of complex coacervates of proteins with flexible and stiff polyelectrolytes |
| A. Basak Kayitmazer, Turkey | |
|
SESSION 1
Conference Room III
Enzymatic methods in glycobiology |
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| Chairperson: Maurice Franssen, Netherlands | |
| 15:30 — 15:50 | Enzyme cascades for the synthesis of multimeric recognition motifs: From fluorescent labeling to runaway block polymerization |
| Wolf-Dieter Fessner, Germany | |
| 15:50 — 16:10 | Diglycosidases: a promising tool for the synthesis of tailored bioactive compounds |
| Javier D. Breccia, Argentina | |
| 16:10 — 16:30 | UDP-sulfoquinovose synthase from the hyperthermoacidophilic archaeon Sulfolobus acidocaldarius |
| Behnam Zolghadr, Austria | |
| 16:30 — 17:00 | Coffee Break |
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Hotel Restaurant |
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SESSION 2
Conference Room III
Carbohydrate synthesis and multivalency |
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| Chairperson: Stefan Oscarson, Ireland | |
| 17:00 — 17:20 | Synthesis and conjugation of multiantennary N-glycan azides |
| Carlo Unverzagt, Germany | |
| 17:20 — 17:40 | C-Glycoside functionalized multivalent ligands as potent inhibitors of DC-SIGN lectin |
| Jitka Moravcová, Czech Republic | |
| 17:40 — 18:00 | Photosensitive multivalent glycomimetics |
| Thisbe K. Lindhorst, Germany | |
| 18:00 — 18:20 | Immunostimulatory glycoclusters derived from β-(1→2)-linked oligomannosides: Recent progress from in vitro and in vivo studies |
| Reko Leino, Finland | |
| 18:20 — 18:40 | Studying the structure of peptide dendrimers by molecular dynamics simulations: branch length, charge, pH and glycosylation |
| Antonio M. Baptista, Portugal | |
| 18:40 — 19:30 | Poster Session 1 |
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all posters will be displayed |
|
| 19:30 — 23:59 | Core Group meeting TBA |
Saturday, 20th April 2013
| 09:00 — 18:00 | Registration |
|
OREA Hotel Pyramida, Prague, Reception Foyer |
|
|
SESSION 3
Conference Room III
Carbohydrate-protein interactions |
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|---|---|
| Chairperson: Lothar Elling, Germany | |
| 09:00 — 09:40 | Siglec ligand decorated nanoparticles for in vivo targeting of immune cells |
| James C. Paulson, USA | |
|
Keynote Lecture |
|
| 09:40 — 10:00 | Influence of lectin valency on surface avidity and glycolipid dynamics in membranes |
| Anne Imberty, France | |
| 10:00 — 10:20 | Tetravalent glycocylopeptide with nanomolar affinity to wheat germ agglutinin |
| Michele Fiore, France | |
| 10:20 — 10:40 | Langerin, a C-type lectin from dendritic cells, can switch from a Ca2+-dependent to a Ca2+-independent binding mode as a function of the glycans |
| Franck Fieschi, France | |
| 10:40 — 11:20 | Coffee Break |
|
Hotel Restaurant |
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|
SESSION 4
Conference Room III
Carbohydrate-nucleic acids interactions; Materials |
|
| Chairperson: Jean-Louis Reymond, Switzerland | |
| 11:20 — 11:40 | Sugar-oligoamides: Chemical tools to study carbohydrate- and glycoprotein-DNA recognition |
| Cristina Vicent, Spain | |
| 11:40 — 12:00 | Glycotargeted gene delivery with cyclodextrins: Making bridges between nucleic acids and lectins |
| José M. García Fernández, Spain | |
| 12:00 — 12:20 | Potent divalent inhibitors containing rigid spacer units |
| Roland J. Pieters, Netherlands | |
| 12:20 — 12:40 | Materials for Glycomics and as Glycomimetics |
| Matthew I. Gibson, UK | |
| 12:40 — 13:00 | Carbohydrate-decorated nanodiamonds for effective sensing and disruption of bacterial and lectin-mediated interactions with glycans |
| Aloysius Siriwardena, France | |
| 13:00 — 14:00 | Lunch |
|
Hotel Restaurant |
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| 14:00 — 15:00 | Poster Session 2 |
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All posters will be displayed. Coffee and drinks will be served. |
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SESSION 5
Conference Room III
Glycomaterials in the medicinal applications |
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| Chairperson: Roland Pieters, Netherlands | |
| 15:00 — 15:20 | Adhesion-targeted therapies in cancer: Modulation of melanoma cells motility and adhesion induced by carbohydrate-based multivalent scaffolds |
| Barbara Richichi, Italy | |
| 15:20 — 15:40 | Sortase-mediated modification of carbohydrate binding proteins for drug delivery |
| Daniel J. Williamson, UK | |
| 15:40 — 16:00 | Facile approach towards synthetic glycolipids: Potential as soft materials and antimicrobial agents |
| Velasco-Torrijos Trinidad, Ireland | |
| 16:00 — 16:20 | New tools for deciphering plant-microbe interactions involving lipochitin oligosaccharides |
| Mikkel B. Thygesen, Denmark | |
| 16:20 — 16:40 | Immunomodulating properties of TLR4-active cationic and anionic amphiphiles |
| Francesco Peri, Italy | |
| 16:40 — 17:00 | Coffee Break |
|
Congress Hall Foyer |
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SESSION 6
Conference Room III
Carbohydrate structures and multivalency |
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| Chairperson: Cristina Nativi, Italy | |
| 17:00 — 17:20 | Synthesis of Lewis b-containing glycoconjugates for investigations of Helicobacter pylori binding to human glycan receptor structures |
| Martina Lahmann & Stefan Oscarson, UK & Ireland | |
| 17:20 — 17:40 | Glycofullerenes as antiadhesive molecules and glycosyltransferase inhibitors |
| Stéphane P. Vincent, Belgium | |
| 17:40 — 18:00 | Imaging cell surface glycosylation in vivo using bioorthogonal ‘double-click’ chemistry |
| Yelena Wainman, UK | |
| 18:00 — 18:20 | Bovine submaxillary mucin (BSM) films: Interaction with lectins and unique non-fouling properties |
| Seunghwan Lee, Denmark | |
| 20:00 — 23:59 | Social Dinner |
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Restaurant Senses, Hotel Prague Castle Lindner (ca 10 min walk, 550 m) |
|
Sunday, 21st April 2013
|
SESSION 7
Conference Room III
Carbohydrates and multivalency |
|
|---|---|
| Chairperson: Olivier Renaudet, France | |
| 09:00 — 09:20 | Incorporation of a calixarene-based glucose functionalised bolaamphiphile in lipid bilayers for multivalent lectin recognition |
| Francesco Sansone, Italy | |
| 09:20 — 09:40 | Impact of the S-Layer and its glycosylation status on the attachment to a surface and the subsequent biofilm formation of Tannerella forsythia |
| Andrea Koerdt, Austria | |
| 09:40 — 10:00 | pH dependent conformational study of a synthetic receptor for molecular recognition of carbohydrates |
| Miguel Machuqueiro, Portugal | |
| 10:00 — 11:00 | Management Committee Meeting |
| 11:00 — 12:00 | Meetings of the Working groups |