Scientific Programme

Electronic version of conference programme (iCalendar format):

Sunday, 21st April 2013

10:00 — 20:00 Registration
OREA Hotel Pyramida, Prague, Reception Foyer
16:30 — 16:45 Opening Ceremony of CBM 10
Vladimír Křen, Czech Republic
OREA Hotel Pyramida Prague, Congress Hall I
Chairperson: Birte Svensson, Denmark
16:45 — 17:30 The differential glycosylation of small and macromolecules: New tools and applications
Jon S. Thorson, USA
Keynote lecture
SESSION 1Congress Hall ISynthesis, structure and function of carbohydrates and glycoconjugates I
Chairperson: Steve Withers, Canada
17:30 — 18:10 The glyco-BioInterface – glycoconjugates for biofunctionalization of biomaterial surfaces
Lothar Elling, Germany
Keynote lecture
19:00 — 22:00 Welcome Reception
Benediktine Monastery Brevnov, Prague

All delegates and accompanying persons registered.

(bus transfer from Pyramida Hotel Prague, departing at 18:30 sharp; takes ca 8 min; buses return back to hotel at 22:15)

Monday, 22nd April 2013

08:00 — 18:00 Registration
OREA Hotel Pyramida, Prague, Reception Foyer
SESSION 2Congress Hall ISynthesis, structure and function of carbohydrates and glycoconjugates II
Chairperson: Antoni Planas, Spain
09:00 — 09:40 Siglecs as sensors of self
James C. Paulson, USA
Keynote lecture
09:40 — 10:00 Supramolecular logic with sugars
Alexander Schiller, Germany
10:00 — 10:20 Fungal β-N-acetylhexosaminidases: Promiscuous synthetic tools
Kristýna Slámová, Czech Republic
10:20 — 10:40 Towards direct glycan/glycopeptide sequencing and identification in glycoproteomic applications
Michaela Ščigelová, Germany
10:40 — 11:00 Microplate screening of Campylobacter jejuni N-oligosaccharyltransferase mutant libraries for activity-relevant residues
Julian Ihssen, Switzerland
11:00 — 11:30 Coffee Break
Congress Hall Foyer
SESSION 3Congress Hall IGlycomics; Systems glycobiology and bioinformatics
Chairperson: Pedro Coutinho, France
11:30 — 11:50 Ten years of exploration of the agarolytic system of Zobellia galactanivorans
Gurvan Michel, France
11:50 — 12:10 In situ visualization of cooperativity among cellulases
Manuel Eibinger, Austria
12:10 — 12:30 Mining for lignocellulases in termite using functional metagenomic
Claire Dumon, France
12:30 — 12:50 Directed evolution, high throughput screening and production of alginate-modifying enzymes with new and targeted properties
Finn L. Aachmann, Norway
Chairperson: Carlos Fontes, Portugal
12:50 — 13:55 Crystal structure of lacto-N-biosidase from Bifidobacterium bifidum
Tasuku Ito, Japan
12:55 — 13:00 α-Amylase families GH57 and GH119 are closely related to each other, whereas family GH38 α-mannosidases is remotely related to both of them
Štefan Janeček, Slovakia
13:00 — 13:05 Fluorescent SNAP-Tag galectin-3 fusion protein as a novel tool in glycobiology
Sophia Böcker, Germany
13:05 — 13:10 Biochemical characterization and structural elucidation of the novel GH31 enzyme of dextran glucanase from Paenibacillus sp. 598K
Hitomi Ichinose, Japan
13:10 — 13:15 Substrate vs. nucleophilically assisted catalysis in retaining glycosyltransferases: Insights from QM/MM calculations
Laura Masgrau, Spain
13:15 — 13:20 The crystal structure of a starch debranching enzyme in complex with a protein inhibitor reveals an extremely tight and novel mode of interaction
Marie Sofie Møller, Denmark
13:20 — 14:30 Lunch
OREA Hotel Pyramida Prague, Restaurant
14:30 — 16:00 Odd number presenters will be available for discussion.
Drinks will be served.
SESSION 4Congress Hall IMechanisms and structure-function relationships of carbohydrate modifying enzymes I
Chairperson: Gideon Davis, UK
16:00 — 16:40 Structures and functions of copper-containing polysaccharide oxygenases
Paul Walton, UK
Keynote lecture
16:40 — 17:00 Mechanism of oxidative cellulose cleavage by the bi-enzymatic system cellobiose dehydrogenase and lytic polysaccharide monooxygenase
Roland Ludwig, Austria
17:00 — 17:20 Recent insights into the structure and function of CBM33-type lytic polysaccharide monooxygenases
Gustav Vaaje-Kolstad, Norway
17:20 — 17:50 Coffee Break
Congress Hall Foyer
SESSION 5Congress Hall IMechanisms and structure-function relationships of carbohydrate modifying enzymes II
Chairperson: Magali Remaud-Simeon, France
17:50 — 18:10 Development of a screening protocol for the identification of surface binding sites in carbohydrate active enzymes
Darrell Cockburn, Denmark
18:10 — 18:30 Switching between O- and C-glycosylation by active-site motif exchange in plant glycosyltransferases
Alexander Gutmann, Austria
18:30 — 18:50 The crystal structure of GH127 β-L-arabinofuranosidase
Shinya Fushinobu, Japan
18:50 — 19:00 Organizatory remarks

Tuesday, 23rd April 2013

09:00 — 19:00 Registration
OREA Hotel Pyramida Prague, Reception Foyer
SESSION 6Congress Hall ISynthesis, structure and function of carbohydrates and glycoconjugates
Chairperson: Marco Moracci, Italy
09:00 — 09:40 Carbohydrates and enzymes: Renaissance of an old interface between chemistry, biology, engineering and medicine
Roland Wohlgemuth, Switzerland
Keynote Lecture
09:40 — 10:00 Diversity of deacetylation of native substrate by acetylxylanesterases
Peter Biely, Slovakia
10:00 — 10:20 Conformational changes as key factors in glycosyltransferase-mediated reactions
Marcelo E. Guerin, Spain
10:20 — 10:40 The molecular mechanism of enzymatic glycosyl transfer with retention of configuration. QM/MM metadynamics investigations
Carme Rovira, Spain
10:40 — 11:00 Engineering improved biocatalysts for efficient syntheses of neo-sialoconjugates
Wolf-Dieter Fessner, Germany
11:00 — 11:30 Coffee Break
Congress Hall Foyer
SESSION 7Congress Hall INew materials from carbohydrates as renewable resources
Chairperson: Sven Pedersen, Denmark
11:30 — 12:10 Oligosaccharide utilization in probiotics for biorefinery based prebiotic design
Maher Abou Hachem, Denmark
Keynote Lecture
12:10 — 12:30 Novel insights into GH20 Bifidobacterium bifidum lacto-N-biosidase enzyme: Characterization and engineering for human milk oligosaccharides synthesis
Magda Faijes, Spain
12:30 — 12:50 β-Rutinosidase – a new tool for glycosylation of phenolic compounds
Petr Marhol, Czech Republic
12:50 — 13:10 Galactose oxidase opens novel ways for tailored natural polysaccharides
Maija Tenkanen, Finlan
13:10 — 13:30 Bio Base Europe Pilot Plant: Open innovation center for carbohydrate bio-engineering
Wim Soetaert, Belgium
13:30 — 14:30 Lunch
OREA Hotel Pyramida Prague, Restaurant
14:30 — 16:00 Even number presenters will be available for discussion.
Drinks will be served.
Chairperson: Bernd Nidetzky, Austria
16:00 — 16:05 (1→4)-α-L-Guluronan in the design and synthesis of biohybrid glycopolymers and chimeric polysaccharides capable of ionotropic gelation
Luca Albertin, France
16:05 — 16:10 α-L-Rhamnosidase: Enzyme suitable for (de)glycosylation
Daniela Šimčíková, Czech Republic
16:10 — 16:15 Chitinases CtcB and CfcI modify the cell wall in sporulating aerial mycelium of Aspergillus niger
Jolanda M. van Munster, Netherlands
16:15 — 16:20 Carbohydrate-based vaccines for breast cancer
Wu Chung-Yi, Taiwan
16:20 — 16:25 Conformational changes and substrate recognition of an uncharacterized glycosidase YgjK belonging to GH63 from Escherichia coli
Miyazaki Takatsugu, Japan
16:25 — 16:30 Synthesis of a Leishmania disaccharide: enzymatic and chemical approaches using partially protected monosaccharides
Yari Cabezas, France
16:30 — 16:35 Investigating the transglycosylation mechanism of an α-L-arabinofuranosidase for pentose-based oligosaccharides synthesis
Bastien Bissaro, France
16:35 — 16:40 Semi rational approach to design new transglycosidases
David Teze, France
SESSION 8Congress Hall ICarbohydrates in health and medicine
Chairperson: Takashi Kuriki, Japan
16:40 — 17:00 The first kinetic and mechanistic analysis of peptidoglycan-O-acetyltransferase, a potential new antibiotic target
Antony J. Clarke, Canada
17:00 — 17:20 Carbohydrate-derived synthetic molecules targeting TLR4: from antisepsis drugs to central nervous system therapeutics
Francesco Peri, Italy
17:20 — 17:40 Structure-function relationships of a glycolipid synthase from Mycoplasma genitalium. A unified computational and experimental approach
Xevi Biarnés, Spain
17:40 — 18:00 Heparosan polysaccharide for drug delivery; a biosuperior alternative to PEGylation
Paul L. DeAngelis, USA
20:00 — 23:59 Social Evening
Prague Castle – Villa Richter, St. Wenceslaus’ Vineyard

(transfer from OREA Hotel Pyramida Prague, departing at 18:30 sharp; buses return back to the hotel at 23:15 – 24.00)

Wednesday, 24th April 2013

09:00 — 13:00 Registration
OREA Hotel Pyramida Prague, Reception Foyer
SESSION 9Congress Hall INew materials from carbohydrates as renewable resources I
Chairperson: Lubbert Dijkhuizen, Netherlands
09:00 — 09:40 The enzymology of microbial hemicellulose utilization in diverse ecological niches: From the forest to the human gut
Harry Brumer, Canada
Keynote Lecture
09:40 — 10:00 Disaccharide phosphorylases as efficient biocatalysts for glycoside synthesis
Karel De Winter, Belgium
10:00 — 10:20 Processivity in glycosyl hydrolases, experimental and molecular dynamics simulations data from the chitinolytic machinery of Serratia marcescens
Morten Sørlie, Norway
10:20 — 10:50 Coffee Break
Congress Hall Foyer
SESSION 10Congress Hall INew materials from carbohydrates as renewable resources II
Chairperson: Vojtěch Spiwok, Czech Republic
10:50 — 11:10 Thermostable glycosidases and glycosynthases as biocatalysts in green chemistry applications
Tania Pozzo, Sweden
11:10 — 11:30 Measurement of cellulase using nitrophenyl-cello-oligosaccharides
Barry McCleary, Ireland
11:30 — 11:50 Engineering of mucin-type O-glycosylation in plants
Richard Strasser, Austria
Chairperson: Ten Feizi, United Kingdom
11:50 — 12:50 The making of N-glycoproteins
Markus Aebi, Switzerland
Keynote Lecture
12:50 — 13:00 Poster Awards, Closing Remarks and invitation to CBM11