Electronic version of conference programme (iCalendar format):
Sunday, 21st April 2013
| 10:00 — 20:00 | Registration |
| OREA Hotel Pyramida, Prague, Reception Foyer | |
| 16:30 — 16:45 | Opening Ceremony of CBM 10 |
| Vladimír Křen, Czech Republic | |
| OREA Hotel Pyramida Prague, Congress Hall I | |
| OPENING LECTURECongress Hall I | |
|---|---|
| Chairperson: Birte Svensson, Denmark | |
| 16:45 — 17:30 | The differential glycosylation of small and macromolecules: New tools and applications |
| Jon S. Thorson, USA | |
| Keynote lecture | |
| SESSION 1Congress Hall ISynthesis, structure and function of carbohydrates and glycoconjugates I | |
| Chairperson: Steve Withers, Canada | |
| 17:30 — 18:10 | The glyco-BioInterface – glycoconjugates for biofunctionalization of biomaterial surfaces |
| Lothar Elling, Germany | |
| Keynote lecture | |
| 19:00 — 22:00 | Welcome Reception |
| Benediktine Monastery Brevnov, Prague
All delegates and accompanying persons registered. (bus transfer from Pyramida Hotel Prague, departing at 18:30 sharp; takes ca 8 min; buses return back to hotel at 22:15) |
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Monday, 22nd April 2013
| 08:00 — 18:00 | Registration |
| OREA Hotel Pyramida, Prague, Reception Foyer | |
| SESSION 2Congress Hall ISynthesis, structure and function of carbohydrates and glycoconjugates II | |
|---|---|
| Chairperson: Antoni Planas, Spain | |
| 09:00 — 09:40 | Siglecs as sensors of self |
| James C. Paulson, USA | |
| Keynote lecture | |
| 09:40 — 10:00 | Supramolecular logic with sugars |
| Alexander Schiller, Germany | |
| 10:00 — 10:20 | Fungal β-N-acetylhexosaminidases: Promiscuous synthetic tools |
| Kristýna Slámová, Czech Republic | |
| 10:20 — 10:40 | Towards direct glycan/glycopeptide sequencing and identification in glycoproteomic applications |
| Michaela Ščigelová, Germany | |
| 10:40 — 11:00 | Microplate screening of Campylobacter jejuni N-oligosaccharyltransferase mutant libraries for activity-relevant residues |
| Julian Ihssen, Switzerland | |
| 11:00 — 11:30 | Coffee Break |
| Congress Hall Foyer | |
| SESSION 3Congress Hall IGlycomics; Systems glycobiology and bioinformatics | |
| Chairperson: Pedro Coutinho, France | |
| 11:30 — 11:50 | Ten years of exploration of the agarolytic system of Zobellia galactanivorans |
| Gurvan Michel, France | |
| 11:50 — 12:10 | In situ visualization of cooperativity among cellulases |
| Manuel Eibinger, Austria | |
| 12:10 — 12:30 | Mining for lignocellulases in termite using functional metagenomic |
| Claire Dumon, France | |
| 12:30 — 12:50 | Directed evolution, high throughput screening and production of alginate-modifying enzymes with new and targeted properties |
| Finn L. Aachmann, Norway | |
| FLASH PRESENTATIONS 1Congress Hall I | |
| Chairperson: Carlos Fontes, Portugal | |
| 12:50 — 13:55 | Crystal structure of lacto-N-biosidase from Bifidobacterium bifidum |
| Tasuku Ito, Japan | |
| 12:55 — 13:00 | α-Amylase families GH57 and GH119 are closely related to each other, whereas family GH38 α-mannosidases is remotely related to both of them |
| Štefan Janeček, Slovakia | |
| 13:00 — 13:05 | Fluorescent SNAP-Tag galectin-3 fusion protein as a novel tool in glycobiology |
| Sophia Böcker, Germany | |
| 13:05 — 13:10 | Biochemical characterization and structural elucidation of the novel GH31 enzyme of dextran glucanase from Paenibacillus sp. 598K |
| Hitomi Ichinose, Japan | |
| 13:10 — 13:15 | Substrate vs. nucleophilically assisted catalysis in retaining glycosyltransferases: Insights from QM/MM calculations |
| Laura Masgrau, Spain | |
| 13:15 — 13:20 | The crystal structure of a starch debranching enzyme in complex with a protein inhibitor reveals an extremely tight and novel mode of interaction |
| Marie Sofie Møller, Denmark | |
| 13:20 — 14:30 | Lunch |
| OREA Hotel Pyramida Prague, Restaurant | |
| POSTER SESSION 1Congress Hall II | |
| 14:30 — 16:00 | Odd number presenters will be available for discussion. |
| Drinks will be served. | |
| SESSION 4Congress Hall IMechanisms and structure-function relationships of carbohydrate modifying enzymes I | |
| Chairperson: Gideon Davis, UK | |
| 16:00 — 16:40 | Structures and functions of copper-containing polysaccharide oxygenases |
| Paul Walton, UK | |
| Keynote lecture | |
| 16:40 — 17:00 | Mechanism of oxidative cellulose cleavage by the bi-enzymatic system cellobiose dehydrogenase and lytic polysaccharide monooxygenase |
| Roland Ludwig, Austria | |
| 17:00 — 17:20 | Recent insights into the structure and function of CBM33-type lytic polysaccharide monooxygenases |
| Gustav Vaaje-Kolstad, Norway | |
| 17:20 — 17:50 | Coffee Break |
| Congress Hall Foyer | |
| SESSION 5Congress Hall IMechanisms and structure-function relationships of carbohydrate modifying enzymes II | |
| Chairperson: Magali Remaud-Simeon, France | |
| 17:50 — 18:10 | Development of a screening protocol for the identification of surface binding sites in carbohydrate active enzymes |
| Darrell Cockburn, Denmark | |
| 18:10 — 18:30 | Switching between O- and C-glycosylation by active-site motif exchange in plant glycosyltransferases |
| Alexander Gutmann, Austria | |
| 18:30 — 18:50 | The crystal structure of GH127 β-L-arabinofuranosidase |
| Shinya Fushinobu, Japan | |
| 18:50 — 19:00 | Organizatory remarks |
Tuesday, 23rd April 2013
| 09:00 — 19:00 | Registration |
| OREA Hotel Pyramida Prague, Reception Foyer | |
| SESSION 6Congress Hall ISynthesis, structure and function of carbohydrates and glycoconjugates | |
|---|---|
| Chairperson: Marco Moracci, Italy | |
| 09:00 — 09:40 | Carbohydrates and enzymes: Renaissance of an old interface between chemistry, biology, engineering and medicine |
| Roland Wohlgemuth, Switzerland | |
| Keynote Lecture | |
| 09:40 — 10:00 | Diversity of deacetylation of native substrate by acetylxylanesterases |
| Peter Biely, Slovakia | |
| 10:00 — 10:20 | Conformational changes as key factors in glycosyltransferase-mediated reactions |
| Marcelo E. Guerin, Spain | |
| 10:20 — 10:40 | The molecular mechanism of enzymatic glycosyl transfer with retention of configuration. QM/MM metadynamics investigations |
| Carme Rovira, Spain | |
| 10:40 — 11:00 | Engineering improved biocatalysts for efficient syntheses of neo-sialoconjugates |
| Wolf-Dieter Fessner, Germany | |
| 11:00 — 11:30 | Coffee Break |
| Congress Hall Foyer | |
| SESSION 7Congress Hall INew materials from carbohydrates as renewable resources | |
| Chairperson: Sven Pedersen, Denmark | |
| 11:30 — 12:10 | Oligosaccharide utilization in probiotics for biorefinery based prebiotic design |
| Maher Abou Hachem, Denmark | |
| Keynote Lecture | |
| 12:10 — 12:30 | Novel insights into GH20 Bifidobacterium bifidum lacto-N-biosidase enzyme: Characterization and engineering for human milk oligosaccharides synthesis |
| Magda Faijes, Spain | |
| 12:30 — 12:50 | β-Rutinosidase – a new tool for glycosylation of phenolic compounds |
| Petr Marhol, Czech Republic | |
| 12:50 — 13:10 | Galactose oxidase opens novel ways for tailored natural polysaccharides |
| Maija Tenkanen, Finlan | |
| 13:10 — 13:30 | Bio Base Europe Pilot Plant: Open innovation center for carbohydrate bio-engineering |
| Wim Soetaert, Belgium | |
| 13:30 — 14:30 | Lunch |
| OREA Hotel Pyramida Prague, Restaurant | |
| POSTER SESSION 2Congress Hall II | |
| 14:30 — 16:00 | Even number presenters will be available for discussion. |
| Drinks will be served. | |
| FLASH PRESENTATIONS 2Congress Hall I | |
| Chairperson: Bernd Nidetzky, Austria | |
| 16:00 — 16:05 | (1→4)-α-L-Guluronan in the design and synthesis of biohybrid glycopolymers and chimeric polysaccharides capable of ionotropic gelation |
| Luca Albertin, France | |
| 16:05 — 16:10 | α-L-Rhamnosidase: Enzyme suitable for (de)glycosylation |
| Daniela Šimčíková, Czech Republic | |
| 16:10 — 16:15 | Chitinases CtcB and CfcI modify the cell wall in sporulating aerial mycelium of Aspergillus niger |
| Jolanda M. van Munster, Netherlands | |
| 16:15 — 16:20 | Carbohydrate-based vaccines for breast cancer |
| Wu Chung-Yi, Taiwan | |
| 16:20 — 16:25 | Conformational changes and substrate recognition of an uncharacterized glycosidase YgjK belonging to GH63 from Escherichia coli |
| Miyazaki Takatsugu, Japan | |
| 16:25 — 16:30 | Synthesis of a Leishmania disaccharide: enzymatic and chemical approaches using partially protected monosaccharides |
| Yari Cabezas, France | |
| 16:30 — 16:35 | Investigating the transglycosylation mechanism of an α-L-arabinofuranosidase for pentose-based oligosaccharides synthesis |
| Bastien Bissaro, France | |
| 16:35 — 16:40 | Semi rational approach to design new transglycosidases |
| David Teze, France | |
| SESSION 8Congress Hall ICarbohydrates in health and medicine | |
| Chairperson: Takashi Kuriki, Japan | |
| 16:40 — 17:00 | The first kinetic and mechanistic analysis of peptidoglycan-O-acetyltransferase, a potential new antibiotic target |
| Antony J. Clarke, Canada | |
| 17:00 — 17:20 | Carbohydrate-derived synthetic molecules targeting TLR4: from antisepsis drugs to central nervous system therapeutics |
| Francesco Peri, Italy | |
| 17:20 — 17:40 | Structure-function relationships of a glycolipid synthase from Mycoplasma genitalium. A unified computational and experimental approach |
| Xevi Biarnés, Spain | |
| 17:40 — 18:00 | Heparosan polysaccharide for drug delivery; a biosuperior alternative to PEGylation |
| Paul L. DeAngelis, USA | |
| 20:00 — 23:59 | Social Evening |
| Prague Castle – Villa Richter, St. Wenceslaus’ Vineyard
(transfer from OREA Hotel Pyramida Prague, departing at 18:30 sharp; buses return back to the hotel at 23:15 – 24.00) |
|
Wednesday, 24th April 2013
| 09:00 — 13:00 | Registration |
| OREA Hotel Pyramida Prague, Reception Foyer | |
| SESSION 9Congress Hall INew materials from carbohydrates as renewable resources I | |
|---|---|
| Chairperson: Lubbert Dijkhuizen, Netherlands | |
| 09:00 — 09:40 | The enzymology of microbial hemicellulose utilization in diverse ecological niches: From the forest to the human gut |
| Harry Brumer, Canada | |
| Keynote Lecture | |
| 09:40 — 10:00 | Disaccharide phosphorylases as efficient biocatalysts for glycoside synthesis |
| Karel De Winter, Belgium | |
| 10:00 — 10:20 | Processivity in glycosyl hydrolases, experimental and molecular dynamics simulations data from the chitinolytic machinery of Serratia marcescens |
| Morten Sørlie, Norway | |
| 10:20 — 10:50 | Coffee Break |
| Congress Hall Foyer | |
| SESSION 10Congress Hall INew materials from carbohydrates as renewable resources II | |
| Chairperson: Vojtěch Spiwok, Czech Republic | |
| 10:50 — 11:10 | Thermostable glycosidases and glycosynthases as biocatalysts in green chemistry applications |
| Tania Pozzo, Sweden | |
| 11:10 — 11:30 | Measurement of cellulase using nitrophenyl-cello-oligosaccharides |
| Barry McCleary, Ireland | |
| 11:30 — 11:50 | Engineering of mucin-type O-glycosylation in plants |
| Richard Strasser, Austria | |
| CLOSING LECTURECongress Hall I | |
| Chairperson: Ten Feizi, United Kingdom | |
| 11:50 — 12:50 | The making of N-glycoproteins |
| Markus Aebi, Switzerland | |
| Keynote Lecture | |
| 12:50 — 13:00 | Poster Awards, Closing Remarks and invitation to CBM11 |